. Author manuscript; available in PMC: 2021 Feb 1.

Published in final edited form as: Biochem Pharmacol. 2019 Dec 6;172:113743. doi: 10.1016/j.bcp.2019.113743

Table 2: Molecular effects of EDCs in the prostate gland, testes, and urinary bladder.

Current studies report the molecular effects and biological endpoints of EDC exposures including enzyme activity, gene regulation, DNA damage and repair, as well as cell proliferation mechanisms. These effects are due to exposures at low and high doses in cell culture and animal models.

	Prostate Gland	Testes	Urinary Bladder
Gene Regulation/Epigenetics	BPA OCP	DES	OCP
Enzyme Activity	BPA DES OCP
DNA Damage	PCB	BPA
Cell Cycle/Cell Proliferation	BPA DES	BPA
Anatomic Features	BPA DES	DES (Frank tumors) PCB