Fig. 4. Off-axis Raman excitation and collection configuration.
(A) Radiance distribution of 830-nm laser in skin model with a configuration of the oblique angle (off-axis) laser illumination. Scale bar, 500 μm. (B) Radiance distribution of 830-nm laser in the same skin model when a conventional probe (on-axis) is applied (the same scale bar applied). (C) Fraction of sampling voxels in off-axis and on-axis configuration as a function of depth in the confined region.