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. 2020 Jan 24;40(1):BSR20193489. doi: 10.1042/BSR20193489

Figure 3. MiR-129-1-3p overexpression weakened DDP resistance in NSCLC.

Figure 3

(A and B) MTT revealed the IC50 value in DDP-resistant cells transfected with miR-129-1-3p mimics; and colony formation assays were used to test cell proliferation and H446/DDP and A549/DDP cells treated with miR-129-1-3p mimics;. (C and D) Flow cytometry analysis and TUNEL were applied to examine apoptosis in cells transfected with miR-129-1-3p mimics and treated with DDP. (E) MiR-129-1-3p expression was detected in cells transfected with miR-129-1-3p inhibitor. (F and G) MTT and colony formation assays were carried out to determine cell proliferation in cells transfected with sh-NORAD#1 and miR-129-1-3p inhibitor and treated with DDP. (H and I) Flow cytometry analysis and TUNEL were carried out to examine apoptosis rate in cells transfected with sh-NORAD#1 and miR-129-1-3p inhibitor and treated with DDP; **P < 0.01.