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. 2020 Jan 24;40(1):BSR20193489. doi: 10.1042/BSR20193489

Figure 5. NORAD knockdown enhanced DDP sensitivity of H446/DDP and A549/DPP cells via restricting SOX4 expression.

Figure 5

(A) SOX4 expression was tested in cells transfected with pcDNA3.1/SOX4. (B and C) MMT and colony formation assays were conducted to measure cell proliferation in cells transfected with sh-NORAD#1 and pcDNA3.1/SOX4 treated with DDP MMT assay revealed the IC50 value for cells under indicted transfections(D and E) Flow cytometry analysis and TUNEL were carried out to measure apoptosis rate in cells transfected with sh-NORAD#1 and pcDNA3.1/SOX4 treated with DDP; **P < 0.01.