Table 1. The summary of prognostic value of ten hub genes and their related pathways.
Gene name | The prognostic value for overall survival rate (P value) | The prognostic value for relapse-free survival rate (P value) | Top ten KEGG pathway enrichment |
---|---|---|---|
PIK3R1 | 0.787 | 0.582 | cAMP signaling pathway Fc epsilon RI signaling pathway Rap1 signaling pathway Fc gamma R-mediated phagocytosis Ras signaling pathway Central carbon metabolism in cancer Proteoglycans in cancer Aldosterone-regulated sodium reabsorption |
CFTR | 0.826 | 0.365 | cAMP signaling pathway |
CSF2 | 0.649 | 0.417 | Fc epsilon RI signaling pathway |
GRM1 | 0.420 | 0.110 | Neuroactive ligand–receptor interaction |
RUNX2 | 0.299 | 0.545 | |
FGFR2 | 0.0141 | 0.0098 | Rap1 signaling pathway Ras signaling pathway Central carbon metabolism in cancer |
CTLA4 | 0.0004 | 0.231 | |
LYN | 0.904 | 0.864 | Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis |
ETS1 | 0.395 | 0.896 | Ras signaling pathway |
PIK3CD | 0.622 | 0.595 | cAMP signaling pathway Fc epsilon RI signaling pathway Rap1 signaling pathway Fc gamma R-mediated phagocytosis Ras signaling pathway Central carbon metabolism in cancer Proteoglycans in cancer Aldosterone-regulated sodium reabsorption |