Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 24;10:1120. doi: 10.1038/s41598-020-57764-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

CDRH3 length differences between OmniRat and human repertoires. (a) CDRH3 length distribution for each species. Species are colored as in (c). CDRH3 lengths were determined using the ImMunoGeneTics (IMGT) numbering scheme. (b) VD insertion length distributions for each species. Species are colored as in (c). (c) DJ insertion length distributions for each species. (d) Average frequency of antibody sequences that use DH family 3 and JH family 6 for each species. Species are colored as in (c). Error bars indicate standard error of the mean. (e) Average DH gene segment length (NT) for wild-type (WT) rat (Rattus norvegicus) in blue and Homo sapiens in gray. Lengths are calculated by counting the number of nucleotides from DH gene segments from the IMGT gene database for each species. Error bars indicate standard error of the mean. (f) Usage frequency of antibody sequences with the given CDRH3 length or longer for each species. Species are colored as in (c).