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. 2020 Jan 24;11:499. doi: 10.1038/s41467-019-14224-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a The number of preys identified for each bait-prey AP-MS complex. Red, rewired preys enhanced in mtKRAS^Hi cells; blue, rewired prey proteins enhanced in mtKRAS^Lo cells. AP-MS complexes are named based on the bait protein and are shown on the x-axis. b Network spoke model view of rewired interactions. Bait–prey interactions identified in both networks with similar prey abundance are shown in gray. Bait–prey interactions that were identified only in EGFRNet^mtKRAS-Hi or EGFRNet^mtKRAS-Lo are shown as solid red or blue edges, respectively. Bait–prey interactions that were detected in both networks but where prey abundance was significantly higher in EGFRNet^mtKRAS-Hi or EGFRNet^mtKRAS-Lo are shown as dotted red or blue edges, respectively. Visit primesdb.eu to explore the complexes in more detail/with greater resolution. c Zoom-in on four nodes that represent mixed, preferential or no rewiring. Source data are provided as a Source Data file.