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. 2020 Jan 24;11:499. doi: 10.1038/s41467-019-14224-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a The number of rewired prey proteins for each bait-prey AP-MS complex that were assessed for differential protein expression between the two cell lines. Rewired prey proteins that were significantly more abundant in the mtKRAS^Hi cells are shown in red. Rewired prey proteins that were significantly more abundant in the mtKRAS^Lo cells are shown in blue. Four selected AP-MS complexes highlighting differentially abundant prey proteins (larger nodes) are also shown. b The number of rewired prey proteins for each bait-prey AP-MS complex that were assessed for differential phosphorylation between the two cell lines. Rewired prey proteins that were significantly more phosphorylated in the mtKRAS^Hi cells are shown in red. Rewired prey proteins that were significantly more phosphorylated in the mtKRAS^Lo cells are shown in blue. Four selected AP-MS complexes highlighting differentially phosphorylated prey proteins (larger nodes) are also shown. c Statistically enriched pathways among the 735 prey proteins involved in rewired interactions. Source data are provided as a Source Data file.