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. 2020 Jan 24;11:513. doi: 10.1038/s41467-019-14258-z

Fig. 6. Erdr1 accelerates wound closure in mouse and human intestinal epithelial cells.

Fig. 6

Scratch-wound assay using Mode-K mouse intestinal epithelial cells cultured ±Erdr1 (1 μg/mL) for 36 h (a picture; b % wound closure). n = 5; representative of three experiments. c–d Cell cycle analysis of Mode-K cells cultured ±Erdr1. n = 3; representative of three experiments (c histogram; d % cell cycle). e–g Ki-67 staining of Mode-K cells stimulated ±Erdr1. n = 3; representative of three experiments. h–i Wound closure of Mode-K cells treated with Erdr1 siRNA or control siRNA (k picture; l % wound closure). n = 7 (control siRNA), n = 8 (Erdr1 siRNA); representative of two experiments. All data are presented as mean ± SD; *P < 0.05, **P < 0.01, ***P < 0.001 by unpaired, two-tailed t-tests.