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. 2020 Jan 24;11:513. doi: 10.1038/s41467-019-14258-z

Fig. 7. Erdr1 promotes the regeneration of Lgr5+ ISCs following radiation-induced injury.

Fig. 7

a Representative images of EGFP staining in ileum sections from Lgr5-EGFP reporter mice housed in SPF conditions. Mice were injected ±Erdr1 daily following 10 Gy irradiation. b Quantification of Lgr5-EGFP+ cells per crypt. n = 60; representative of three experiments. c Representative images of Ki-67 staining in ileum and colon sections (pink, Ki-67; blue, DAPI). d Quantification of Ki-67 positive cells per crypt from the ileum (top) and colon (bottom). n = 60; representative of three experiments. All data are presented as mean ± SD; *P < 0.05, **P < 0.01, ***P < 0.001 by one-way ANOVA with Tukey’s multiple comparison test.