Table 1.
Clinicodemographic characteristics of patients with bipolar II disorder (BD-II) and healthy controls.
| BD-II | Healthy controls | Χ2 or t | P value | |
|---|---|---|---|---|
| n | 102 | 118 | ||
| Age (mean, SD) | 35.5 ± 11.6 | 31.0 ± 8.4 | 3.3 | <0.001 |
| Gender (M/F) | 38/64 | 61/57 | 4.6 | 0.03 |
| Onset age (years old) | 14.5 ± 3.8 | N/A | ||
| HAMD | 14.2 ± 3.4 | N/A | ||
| YMRS | 13.1 ± 2.4 | N/A | ||
| miR-7-5p (delta Ct) | −17.5 ± 5.3 | −22.6 ± 5.8 | 6.6 | <0.001 |
| miR-23b-3p (delta Ct) | −12.3 ± 2.6 | −13.3 ± 3.0 | 2.5 | 0.013 |
| miR-142-3p (delta Ct) | −3.4 ± 0.8 | −5.1 ± 1.4 | 11.2 | <0.001 |
| miR-145-5p (delta Ct) | −3.9 ± 1.4 | −4.1 ± 1.7 | 1.1 | 0.28 |
| miR-221-5p (delta Ct) | −9.4 ± 0.8 | −10.8 ± 1.8 | 7.6 | <0.001 |
| miR-370-3p (delta Ct) | −17.6 ± 8.1 | −24.2 ± 6.2 | 6.6 | <0.001 |
HAMD: Hamilton depression rating scale.
YMRS: Young manic rating scale.
N/A: not available.
SD: standard deviation.
We used t-test for continuous variables and chi-square test for categorical variables.