Table 1.

Enriched gene ontology (GO) terms and genes fall into clusters.

Term	Description	LogP	Log (q-Value)	Symbols
GO:0030198	extracellular matrix organization	−14.18	−9.87	ACAN, COL4A2, COL9A3, HAPLN1, DAG1, FOXC1, HSPG2, CCN1, ITGA6, ITGA3, LAMB3, MELTF, PDGFA, SOX9, TNXB, ITGA10, ADAMTSL2, SPINT2, ABI3BP, GREM1, NTN4, THSD4, SCUBE1, OLFML2A, DMD, GDF5, ADAMTS1, P3H2, COL10A1, MMP17, CAPNS2, CTRB2
GO:0001525	angiogenesis	−9.15	−5.53	COL4A2, CSPG4, DAG1, FGF1, FOXC1, HGF, HOXA3, HSPG2, CCN1, LEPR, MFGE8, NOTCH3, PDGFA, PTGIS, FZD8, APLN, ADGRG1, RAMP1, ESM1, GREM1, HIPK2, RASIP1, ISM1, WNT11, ERRFI1, ADRB2, DOK1, EFNB1, GALNT3, IGFBP2, PTGIR, SOX9, MTSS1, PLCB1, NGEF, RHBDF2, SPRY4
GO:0070848	response to growth factor	−7.29	−4.01	RUNX3, COL4A2, FGF1, FOXC1, GALNT3, GDF10, HGF, CCN1, ITGA3, PENK, SOX5, SOX9, GDF5, APLN, ADAMTSL2, SPINT2, DKK1, BAMBI, GREM1, DKK3, HIPK2, ERRFI1, SPRY4, INHBB
GO:0001503	ossification	−6.64	−3.50	ACP5, ADRB2, FOXC1, GDF10, HGF, CCN1, P2RX7, PENK, SRGN, SOX9, WNT3, WNT11, GDF5, DKK1, GREM1, SMOC1, ACAN, RUNX3, HAPLN1, HOXA3, HOXD10, SOX5, SPNS2, CSPG4, LEPR
GO:0003002	regionalization	−6.33	−2.93	EMX1, EVX1, FGF1, FOXC1, HOXA3, HOXA10, HOXD10, LFNG, WNT3, LHX3, ADGRG1, LHX2, ZEB2, SPRY1, DKK1, GREM1, FOXB1, HIPK2, HES2, GSC, SP8, EFNB1, SHROOM3
GO:0048598	embryonic morphogenesis	−5.72	−2.71	COL4A2, DAG1, FOXC1, HOXA3, HOXD10, CCN1, ITGA3, LAMB3, SOX9, WNT3, WNT11, GDF5, APLN, LHX2, SPINT2, DKK1, HIPK2, SHROOM3, ACAN, ADAMTS1, GREM1, HSPB7, ALPK3, SCUBE1, PDGFA
GO:0035272	exocrine system development	−5.57	−2.58	DAG1, FOXC1, HGF, PDGFA, SOX9, NTN4, FGF1, SPINT2, RASIP1, WNT11, DKK1, GREM1, CYP19A1, HOXA3, WNT3, APLN, DKK3, PLCB1, PRR5L, PEAR1, LHX2
GO:0072006	nephron development	−5.52	−2.55	FGF1, FOXC1, ITGA3, NOTCH3, PDGFA, PODXL, SOX9, WNT11, MTSS1, DAG1, HGF, CCN1, WNT3, LHX2, SPINT2, DKK1, RIPK4, RASIP1, SHROOM3, NTN4, CYP19A1, ITGA6, CRLF1, ADAMTS1, ADAMTSL2, ERRFI1, PGF, SPRY1
GO:2000272	negative regulation of signaling receptor activity	−5.38	−2.19	DKK1, DKK3, ERRFI1, LYNX1, MTRNR2L7, MTRNR2L3, MTRNR2L8, MTRNR2L9, ADRB2, MUC4, SHANK2, GREM1
GO:0043408	regulation of mitogen-activated protein kinase cascade	−5.17	−2.35	ADRB2, CSPG4, DAG1, FGF1, GDF10, HGF, CCN1, INHBB, IRAK2, P2RX7, PDGFA, GDF5, FZD8, DKK1, PLCB1, GREM1, HIPK2, ERRFI1, NDRG2, SPRY4, DMD, RASIP1, PRR5L, CAMK2N2, WNT11
GO:0031128	developmental induction	−5.08	−2.30	FGF1, SOX9, WNT3, DKK1, HIPK2, COL4A2, DAG1, FOXC1, ITGA3, LAMB3, WNT11, APLN, ADRB2, IGFBP2, P2RX7, FZD8, SHANK2, PLCB1, BAMBI, GREM1, DKK3, NDRG2, LHX2, ANK1, HGF, HOXD10, HSPG2, NOTCH3, SOX5, RAMP1, GDF5
GO:0061035	regulation of cartilage development	−4.54	−1.84	CCN1, SOX5, SOX9, WNT11, GDF5, GREM1, ACAN, RUNX3, HOXA3, PDGFA, ANXA2, GDF10, SRGN, DKK1
GO:0072497	mesenchymal stem cell differentiation	−4.52	−1.83	SOX5, SOX9, WNT3, FOXC1, TNXB, THSD4, ADAMTSL2, ERRFI1, DKK1