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. 2019 Dec 31;21(1):287. doi: 10.3390/ijms21010287

Table 2.

Metabolic pathways involved in neutrophil functions.

Neutrophil Function Metabolic Requirements References
Phagocytosis Glycolysis [18]
ROS production (NOX) PPP, Glutaminolysis [63,72]
Degranulation Glycolysis [12,110]
NET formation PPP, Glycolysis [14,63]
Chemotaxis/migration Glycolysis, mitochondrial metabolism [76,77,111]

ROS—reactive oxygen species; NOX—NADPH oxidase; NET—neutrophil extracellular trap; PPP—pentose phosphate pathway.