Table 2.
Neutrophil Function | Metabolic Requirements | References |
---|---|---|
Phagocytosis | Glycolysis | [18] |
ROS production (NOX) | PPP, Glutaminolysis | [63,72] |
Degranulation | Glycolysis | [12,110] |
NET formation | PPP, Glycolysis | [14,63] |
Chemotaxis/migration | Glycolysis, mitochondrial metabolism | [76,77,111] |
ROS—reactive oxygen species; NOX—NADPH oxidase; NET—neutrophil extracellular trap; PPP—pentose phosphate pathway.