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. 2019 Dec 31;21(1):285. doi: 10.3390/ijms21010285

Figure 5.

Figure 5

VEGFR-1 expression in decidua and trophoblast of first trimester pregnancy. In decidua of G-CSF treated group (A), in the no treated RPL group (B) and Control pregnancies (C) there was the same staining levels in the epithelial cells but no in the stroma for VEGFR-1 (brown color) (400×). In trophoblast of G-CSF treated samples (D), the syncytiotrophoblast was moderately positive to VEGFR-1 (brown color) (400×). In trophoblast of RPL no-treated samples (E), the syncytiotrophoblast was strongly positive to VEGFR-1, more than in other two groups (400×). In trophoblast of Control samples (F), the syncytiotrophoblast was moderately positive to VEGFR-1 (brown color) similar to G-CSF treated samples (400×). The graph (G) showed immunohistochemical staining semi quantitative HSCORE for VEGFR-1 (Charts display median and quartiles with whiskers showing the range): There was statistically significant differences between G-CSF vs. RPL (* p < 0.001) and RPL vs. Control (** p < 0.001).