OI 10.21	Temperature: influences the fatigue life of bone [176,177].
OI 10.22	Water content: influences the stiffness, strength and toughness of bone [179,180]; the Young’s Modulus of dead (dry) and living (wet) bones tend to be different [178]. Furthermore, viscoelastic [181] properties of bones are also influenced by the water content. The water content of bone is related to the molecular scale, see Section 13.
OI 10.23	Mineral content: porosity and mineral content influence bone Young’s Modulus [182,183,184]. The mineral content of bone is related to the molecular scale, see Section 13
OI 10.24	Bone density: exhibits a p-value based highly significant positive correlation with bone fatigue life [176,177]. Furthermore, density influences bone stiffness and strength [185].
OI 10.25	Porosity: alongside bone mineral content, influences bone Young’s Modulus [182].