B6	C57BL/6J
CESA	Comitato Etico per la Sperimentazione Animale
DE	Definitive endoderm
E7.5	Embryonic day 7.5
ESCs	Embryonic stem cells
mESCs	Mouse embryonic stem cells
PS	Primitive streak
EMT	Epithelial-to-mesenchymal transition
MET	Mesenchymal-to-epithelial transition
VE	Visceral endoderm
PFE	Posterior foregut endoderm
DPB	Dorsal pancreatic bud
SLRP	Small leucine-rich repeat protein
IPGTT	Intraperitoneal glucose tolerance test
KO	Knock-out
Nepn	Nephrocan
WT	Wild-type
CRISPR/Cas9	(CRISPR)/CRISPR-associated systems 9
UTR	Untranslated region
RT-PCR	Reverse transcriptase-polymerase chain reaction
RT-qPCR	Real Time-quantitative polymerase chain reaction
SD	Standard Deviation
FRT	Flip-recombinase targets
PGK	Phosphoglycerate kinase 1
PAM	Protospacer adjacent motif