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Experimental study of renal functionality. Evaluation of urinary parameters in 24 h urine output of Nepn−/− mice compared to Nepn+/+ in a group of 4–6 months old mice.
| Urinary Parameters | Nepn +/+ | Nepn −/− |
|---|---|---|
| Urinary Volume (mL) | 1.86 ± 0.37 | 1.63 ± 0.25 |
| Creatinine excretion (µmol/g body weight) | 0.24 ± 0.03 | 0.23 ± 0.01 |
| Na+/creatinine | 22.75 ± 4.16 | 27.92 ± 4.41 |
| K+/creatinine | 20.36 ± 3.95 | 18.14 ± 2.23 |
| Cl−/creatinine | 62.91 ± 6.43 | 72.34 ± 3.43 |
| Creatinine clearence | 113.16 ± 14.91 | 97.56 ± 11.33 |
