APC |
antigen presenting cells |
CIITA |
class II transactivator |
COX |
cyclooxygenase |
CREBBP |
cAMP-response element binding protein (CREB) binding protein |
DNMTs |
DNA-methyltransferases |
FOXP |
“forkhead box P” transcription factor |
GAD |
glutamic acid decarboxylase |
HATs |
histone-acetyltransferases |
HDACs |
histone-deacetylases |
HLA |
human leukocyte antigen |
HPA |
hypothalamic-pituitary-adrenal |
INS |
insulin |
LADA |
latent autoimmune diabetes in adults |
MBD |
methyl-CpG-binding proteins |
mTOR |
mammalian/mechanistic target of rapamycin (serine-threonine kinase) |
MZ twins |
monozygotic twins |
NF-κB |
nuclear factor kappa B |
NFKB1A |
gene for the inhibitor of NF-κB, IκBα |
NOD mice |
non-obese diabetic mice |
NRF1 |
nuclear respiratory factor 1 |
PDCD4 |
programmed cell death protein 4 |
PTPN22 |
protein tyrosin-phosphatase non-receptor-type 22 |
RFXAP |
regulatory factor X associated protein |
RISC |
RNA-induced silencing complex |
SAM |
S-adenosyl methionine donor |
SNP |
single nucleotide polymorphism |
T1DM |
type 1 diabetes mellitus |
Tregs |
regulatory T cells |
TSA |
trichostatin A |
VNTR |
variable number tandem repeat |