Table 3.
The epigenetic changes found in patients with T1DM: RNA interference.
| Publication | Specific Target | Type of Cells | Results |
|---|---|---|---|
| (1st Author + Year) | |||
| Hezova, 2010 [54] | genome-wide | Tregs | ↑ miR-510 |
| ↓ miR-342 + miR-191 | |||
| de Jong, 2016 [55] | genome-target | CD8+ T cells | ↑ miR-98, miR-23b, miR-590 |
| Sebastiani, 2011 [56] | miR-326 | lymphocytes | ↑ miR-326 |
| Salas-Pérez, 2013 [57] | miR-21a + miR-93 | mononuclear cells | ↓ miR-21a + miR-93 |
| Yang, 2015 [59] | genome-wide | mononuclear cells | ↓ miR-146 |
| differences in 26 miRNAs |
↓ Decrease of miRNA expression. ↑ Increase of miRNA expression.