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. 2019 Dec 27;21(1):203. doi: 10.3390/ijms21010203
wt,tg corin-WT/DCM,
tg,tg corin-Tg(i)/DCM
wt,wt WT/WT
Corin-Tg (i) corinS1052A-Tg
Tg transgenic
WT wild-type
HF heart failure
rEF reduced ejection fraction
HFrEF heart failure with reduced ejection fraction
DCM dilated cardiomyopathy
RAAS renin-angiotensin-aldosterone-system
NP natriuretic peptide
ANP atrial natriuretic peptide
BNP b-type natriuretic peptide
Ang II angiotensin II
Aldo aldosterone
Ang (1–7) angiotensin (1–7)
NEP neprilysin
cGMP cyclic guanosine monophosphate
GSK3β glycogen synthase kinase 3β
pSer9-GSK3β glycogen synthase kinase 3β phosphorylated at Ser9
ELISA enzyme-linked immunosorbent assay
qRT-PCR quantitative real-time polymerase chain reaction
AU arbitrary units
SEM standard error of the mean
CD cytoplasmic domain
TM transmembrane
LDLR low density lipoprotein receptor
Fz frizzled
SR macrophage scavenger receptor
H histidine
D aspartate
S serine
A alanine
BW body weight
HW/BW heart weight to bodyweight ratio
LW/BW lung weight to bodyweight ratio
QMR quantitative magnetic resonance
ECW extracellular water
LV left ventricle
EF ejection fraction
FS fraction shortening
CO cardiac output
SV stroke volume
BPM beats per minute
LVIDd left ventricular internal diameter, diastole
LVIDs left ventricular internal diameter, systole
LVMc left ventricular mass corrected
IVSd interventricular septum, diastole
LVPWd left ventricular posterior wall, diastole
PA pulmonary artery
AA ascending aorta
PE pleural effusion