wt,tg |
corin-WT/DCM, |
tg,tg |
corin-Tg(i)/DCM |
wt,wt |
WT/WT |
Corin-Tg (i) |
corinS1052A-Tg |
Tg |
transgenic |
WT |
wild-type |
HF |
heart failure |
rEF |
reduced ejection fraction |
HFrEF |
heart failure with reduced ejection fraction |
DCM |
dilated cardiomyopathy |
RAAS |
renin-angiotensin-aldosterone-system |
NP |
natriuretic peptide |
ANP |
atrial natriuretic peptide |
BNP |
b-type natriuretic peptide |
Ang II |
angiotensin II |
Aldo |
aldosterone |
Ang (1–7) |
angiotensin (1–7) |
NEP |
neprilysin |
cGMP |
cyclic guanosine monophosphate |
GSK3β |
glycogen synthase kinase 3β |
pSer9-GSK3β |
glycogen synthase kinase 3β phosphorylated at Ser9 |
ELISA |
enzyme-linked immunosorbent assay |
qRT-PCR |
quantitative real-time polymerase chain reaction |
AU |
arbitrary units |
SEM |
standard error of the mean |
CD |
cytoplasmic domain |
TM |
transmembrane |
LDLR |
low density lipoprotein receptor |
Fz |
frizzled |
SR |
macrophage scavenger receptor |
H |
histidine |
D |
aspartate |
S |
serine |
A |
alanine |
BW |
body weight |
HW/BW |
heart weight to bodyweight ratio |
LW/BW |
lung weight to bodyweight ratio |
QMR |
quantitative magnetic resonance |
ECW |
extracellular water |
LV |
left ventricle |
EF |
ejection fraction |
FS |
fraction shortening |
CO |
cardiac output |
SV |
stroke volume |
BPM |
beats per minute |
LVIDd |
left ventricular internal diameter, diastole |
LVIDs |
left ventricular internal diameter, systole |
LVMc |
left ventricular mass corrected |
IVSd |
interventricular septum, diastole |
LVPWd |
left ventricular posterior wall, diastole |
PA |
pulmonary artery |
AA |
ascending aorta |
PE |
pleural effusion |