iPSC	Induced pluripotent stem cell
CENV	Cell-engineered nanovesicle
EV	Extracellular vesicle
ROS	Reactive oxygen species
HDF	Human dermal fibroblast
qPCR	Quantitative real-time polymerase chain reaction
RT-PCR	Reverse transcriptase polymerase chain reaction
ECM	Extracellular matrix
PSC	Pluripotent stem cell
CDK	Cyclin-dependent kinase
hUCMSC	Human umbilical cord mesenchymal stem cell
hPlaMSC	Human placenta mesenchymal stem cell
mESC	Murine embryonic stem cell
SA- β-Gal	Senescence-associated β-galactosidase
NTA	Nanoparticle tracking analysis
TEM	Transmission electron microscopy
DLS	Dynamic light scattering
FBS	Fetal bovine serum
DMEM	Dulbecco’s modified Eagle’s medium
PBS	Phosphate buffered saline
WST-8	Water-soluble tetrazolium-8
MMP	Matrix metalloproteinase