IRES	Internal ribosome entry site
ITAF	IRES trans-acting factor
ALS	Amyotrophic lateral sclerosis
hnRNP A1	Heterogeneous nuclear ribonucleoprotein A1
mTOR	Mechanistic target of rapamycin
mTORC	Mechanistic target of rapamycin complex
CNS	Central nervous system
PI3K	Phosphatidylinositol 3-kinase
EGFR	Epidermal growth factor receptor
PTEN	Phosphatase and tensin homolog
AKT/PKB	Protein kinase B
SPR	Surface plasmon resonance
FDA	Food and drug administration, United States
PDX	Patient derived xenograft
RNP	Ribonucleoprotein
RRM	RNA recognition motif
GST	Glutathione S-transferase
FITC	Fluorescein isothiocyanate
SCID	Severe combined immunodeficient
TUNEL	Terminal deoxynucleotidyl transferase dUTP nick end labeling
qrt-PCR	Quantitative reverse transcription polymerase chain reaction