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. 2019 Dec 28;21(1):219. doi: 10.3390/ijms21010219

Table 6.

Docking scores of our designed cyclopropane hybrid derivatives in HDAC4 and HDAC5 receptors.

Compound HDAC4
Docking Score
−log10(Kd)
Log p-Value
H16 12.35 2.07
H17 12.12 0.90
H1 11.58 1.19
H4 11.16 0.96
H6 10.73 3.72
H8 10.66 1.05
H12 10.66 2.77
H13 10.25 1.84
H15 9.99 1.88
H10 9.94 2.77
H11 9.53 2.86
40 8.82 2.72
49 8.45 2.14
31 8.22 2.07
25 8.00 3.76
30 7.98 2.39
22 7.73 3.34
15 7.43 2.97