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The hydrophobic and aromatic interaction network with the key residue Phe215 in (a) the CD44s stem region, cluster 1; (b) the CD44s stem region, cluster 2; and (c) the CD44v6 stem region, cluster 1. The residues involved in the hydrophobic and aromatic interactions are colored orange and are shown in sticks with spheres (left) and surfaces (right).
