Table 1.

Interaction energy (kcal/mol) between the side chain of Phe215 and the residues that were involved in the persistent hydrophobic contacts listed in Table S4. All of the values are presented as mean ± SD.

	van der Waals Energy	Electrostatic Energy	Interaction Energy
CD44s, cluster 1	−1.196 ± 1.058	−0.1625 ± 0.3979	−1.358 ± 1.243
CD44s, cluster 2	−1.534 ± 0.8957	0.1097 ± 0.2475	−1.424 ± 0.9442
CD44v6, cluster 1	−2.394 ± 1.445	−0.08138 ± 0.2759	−2.476 ± 1.485