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. 2019 Dec 25;21(1):155. doi: 10.3390/ijms21010155

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Electron microscopic analyses of Atg7 deficient renal proximal tubular cells. The renal proximal tubular cells of 2-month-old Atg7^flox/flox;KAP-Cre⁺ (A,B,D–F) and Atg7^flox/flox (C) mice were investigated with a transmission electron microscopy. (B) is higher magnification of area. Black asterisks indicated degenerated mitochondria. (A) (white box). (E,F) are higher magnification of areas (white boxes 1 and 2, respectively) in (D). Asterisks in (E) indicated peroxisome-like structures in the multi-lamellar bodies. Arrows indicate lysosome like structures in the multi-lamellar bodies.