Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Dec 29;21(1):236. doi: 10.3390/ijms21010236

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

IL-9 has an impact on the characteristics of murine bone-marrow-derived cultured mast cells. The combination of SCF and IL-9 induced the expression of Mcpt1 and Mcpt2 in murine bone-marrow-derived cultured mast cells, as reported previously, and significantly suppressed the histamine synthesis and storage. IL-9-modified mast cells (MCs/IL-9) were less sensitive to ATP and the antigen in degranulation. The presence of fibroblasts recovered the histamine synthesis and tryptase expression.