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. 2019 Dec 18;21(1):10. doi: 10.3390/ijms21010010
AE(s) Adverse effect(s)
AKT Protein kinase B
ATC Anaplastic thyroid cancer
c-KIT Stem cell factor receptor
DTC Differentiated thyroid cancer
EGFR Epidermal growth factor receptor
ERK Mitogen-activated protein kinase
FGFR Fibroblast growth factor receptor
FLT-3 FMS-like tyrosine kinase 3
FTC Follicular thyroid cancer
HCC Hürthle cell carcinoma
HIF Hypoxia-inducible factor
MEK Mitogen-activated protein kinase kinase
MET Hepatocyte growth factor receptor
MKI(s) Multikinase inhibitor(s)
MTC Medullary thyroid cancer
mTOR Mammalian target of rapamycin
N/A Not available
N/R Not reached
OS Overall survival
PDGFR Platelet-derived growth factor receptor
PDTC(s) Poorly differentiated thyroid cancer(s)
PFS Progression-free survival
PGF Placental growth factor
PI3K phosphoinositide 3-kinase
PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses
PTC Papillary thyroid cancer
RAF Rapidly accelerated fibrosarcoma kinase
RAI Radioactive iodine
RAS Rat sarcoma protein
RET Rearranged during transfection
RECIST Response Evaluation Criteria in Solid Tumors
RR Response rate
TSH Thyroid-stimulating hormone
VEGF Vascular endothelial growth factor
VEGFR Vascular endothelial growth factor receptor
VHL Von Hippel–Lindau tumor suppressor