Table 3.
Distribution frequency of the clinical status and FGFR4 rs2011077 genotype frequencies in 428 UCC patients.
| Variable | FGFR4 (rs2011077) | |||
|---|---|---|---|---|
| TT (%) (n = 110) | TC + CC (%) (n = 318) | OR (95% CIs) | P Value | |
| Stage | ||||
| pTa–pT2 | 82 (74.5%) | 199 (62.6%) | 1.000 (reference) | |
| pT3–pT4 | 28 (25.5%) | 119 (37.4%) | 1.751 (1.078–2.846) | 0.023 * |
| Tumor T status | ||||
| Ta–T2 | 82 (74.5%) | 204 (64.2%) | 1.000 (reference) | |
| T3–T4 | 28 (25.5%) | 114 (35.8%) | 1.637 (1.006–2.662) | 0.046 * |
| Lymph node status | ||||
| N0 | 101 (91.8%) | 277 (87.1%) | 1.000 (reference) | |
| N1 + N2 | 9 (8.2%) | 41 (12.9%) | 1.661 (0.779–3.540) | 0.185 |
| Metastasis | ||||
| M0 | 107 (97.3%) | 307 (96.5%) | 1.000 (reference) | |
| M1 | 3 (2.7%) | 11 (3.5%) | 1.278 (0.350–4.668) | 0.710 |
| Histopathologic grading | ||||
| Low grade | 20 (18.2%) | 33 (10.4%) | 1.000 (reference) | |
| High grade | 90 (81.8%) | 285 (89.6%) | 1.919 (1.049–3.511) | 0.032 * |
* Bold font indicates statistical significance (p < 0.05). CIs: Confidence intervals; OR: Odds ratio with their 95% confidence intervals were estimated by logistic regression models.