Table 4.
Distribution frequency of the clinical status and FGFR4 rs1966265 genotype frequencies in 428 UCC patients.
| Variable | FGFR4 (rs1966265) | |||
|---|---|---|---|---|
| AA (%) (n = 107) | AG + GG (%) (n = 321) | OR (95% CIs) | P-Value | |
| Stage | ||||
| pTa–pT2 | 80 (74.8%) | 201 (62.6%) | 1.000 (reference) | |
| pT3–pT4 | 27 (25.2%) | 120 (37.4%) | 1.769 (1.082–2.891) | 0.022 * |
| Tumor T status | ||||
| Ta–T2 | 80 (74.8%) | 206 (64.2%) | 1.000 (reference) | |
| T3–T4 | 27 (25.2%) | 115 (35.8%) | 1.654 (1.011–2.706) | 0.044 * |
| Lymph node status | ||||
| N0 | 98 (91.6%) | 280 (87.2%) | 1.000 (reference) | |
| N1 + N2 | 9 (8.4%) | 41 (12.8%) | 1.594 (0.748–3.400) | 0.224 |
| Metastasis | ||||
| M0 | 104 (97.2%) | 310 (96.6%) | 1.000 (reference) | |
| M1 | 3 (2.8%) | 11 (3.4%) | 1.230 (0.337–4.495) | 0.754 |
| Histopathologic grading | ||||
| Low grade | 20 (18.7%) | 33 (10.3%) | 1.000 (reference) | |
| High grade | 87 (81.3%) | 288 (89.7%) | 2.006 (1.096–3.674) | 0.022 * |
* Bold font indicates statistical significance (p < 0.05). CIs: Confidence intervals. OR: Odds ratio with their 95% confidence intervals were estimated by logistic regression models.