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Inhibitors of XPO1 and PAK4 suppress thyroid cancer cell proliferation in vitro. 8505C cells were seeded in 96 well plates at a density of 5000 cells per well. The next day cells were exposed to increasing concentrations of either (A) KPT-330, (B) KPT-8602 or (C) KPT-9274 for 72 h. At the end of treatment, MTT assay was performed according to the standard procedure described in methods section. Each point represents six replicates.
