TABLE 1.

dMRI measures of 40 patients demonstrating reduction in ventricular size and MD measures following treatment for hydrocephalus

Measure	Scan Time	Hydro		PHH		CH		Control		Pairwise Comparisons
		Mean	SD	Mean	SD	Mean	SD	Mean	SD	Hydro-Control	PHH-Control	CH-Control	PHH-CH
FOHR	Pre-Tx	0.54	0.09	0.51	0.07	0.57	0.10	0.34	0.06	<0.001*	<0.001*	<0.001*	0.062
	5 mos	0.51	0.10	0.49	0.10	0.53	0.11	—	—	—	—	—	0.293
	14 mos	0.44	0.10	0.44	0.11	0.44	0.09	0.38	0.04	0.107	0.154	0.087	1.000
PLIC MD × 10−3 mm2/sec	Pre-Tx	1.00	0.18	1.09	0.17	0.92	0.16	0.85	0.06	0.027*	0.001*	0.247	0.007*
	5 mos	0.94	0.11	0.98	0.12	0.90	0.08	—	—	—	—	—	0.032
	14 mos	0.85	0.07	0.85	0.06	0.84	0.08	0.84	0.04	0.702	0.678	1.000	0.695
gCC MD × 10−3 mm2/sec	Pre-Tx	1.10	0.21	1.22	0.17	0.97	0.17	0.98	0.14	0.135	0.003*	0.886	<0.001*
	5 mos	1.10	0.18	1.16	0.19	1.03	0.15	—	—	—	—	—	0.039*
	14 mos	0.94	0.11	0.94	0.13	0.94	0.09	1.00	0.10	0.169	0.269	0.147	1.000

Hydro = hydrocephalus; Tx = treatment; — = between-group comparison not performed as follow-up measures were not available for the control group at 5 months. The hydrocephalus group combines patients with CH and patients with PHH. dMRI studies were obtained prior to hydrocephalus treatment (Pre-Tx) and at median follow-up times of 5 and 14 months.

^*Benjamini-Hochberg corrected p values with p < 0.05 set as significant.