Table 2.
The quality of evidence.
| Outcomes | Effect | Number of participants (studies) | Quality of the evidence (GRADE) | |
|---|---|---|---|---|
| Relative effect (95% CI) | Absolute effect (95% CI) | |||
| LKSS | — | MD 8.67 higher (6.59 to 10.75 higher) | 744 (7 studies) | ⊕⊕⊝⊝ low1,3 |
| VAS | — | MD 1.39 lower (1.99 to 0.79 lower) | 670 (7 studies) | ⊕⊝⊝⊝ very low1,2,3 |
| ER | RR 1.23 (1.15 to 1.31) | 173 more per 1000 (from 113 more to 233 more) | 750 (8 studies) | ⊕⊕⊝⊝ low1,2 |
1High risk of performance bias; one of the studies describe the allocation concealment. 2Adverse events were not sufficiently reported. 3Significant heterogeneity.