Table 2.
Association between KCNQ1 rs2237895 and different lipid parameters and T2DM.
| Variables | β (SE) | PC (%) (95% CI) | P |
|---|---|---|---|
| Lipid parameters | |||
| TC | 0.049 (0.021) | 5.01 (0.80, 9.38) | 0.019 |
| TG | -0.018 (0.028) | -1.75 (-7.03, 3.82) | 0.530 |
| LDL-C | 0.039 (0.016) | 3.93 (0.64, 7.33) | 0.019 |
| HDL-C | 0.015 (0.007) | 1.51 (0.18, 2.86) | 0.026 |
| Apo-A | 0.015 (0.007) | 1.51 (0.04, 3.01) | 0.045 |
| Apo-B | 0.015 (0.006) | 1.51 (0.38, 2.66) | 0.009 |
| T2DM | |||
| Model 1 | 0.154 (0.028) | 16.65 (10.43, 23.22) | <0.001 |
| Model 2 | 0.163 (0.028) | 17.64 (11.30, 24.35) | <0.001 |
β: estimate; SE: standard error; PC: percentage change; CI: confidence interval; TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Apo-A: apolipoprotein A; Apo-B: apolipoprotein B; T2DM: type 2 diabetes mellitus. Notes: models for lipid parameters and T2DM model 1 were adjusted for age, sex, smoking and drinking status, hypertension, coronary heart disease, and body mass index. T2DM model 2 was adjusted for age, sex, smoking and drinking status, hypertension, coronary heart disease, body mass index, TC, TG, LDL-C, and HDL-C. P values < 0.05 are shown in bold.