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. Author manuscript; available in PMC: 2020 Jan 25.
Published in final edited form as: Rheum Dis Clin North Am. 2017 Aug;43(3):401–414. doi: 10.1016/j.rdc.2017.04.006

Table 2.

Association analysis of SNPs and amino acids at position 97 of HLA-B.

Amino acid residue Multivariate OR (95% CI) P-value Classical HLA-B Allele
Asparagine (N) 16.51 (15.43–17.69) < 1 × 10−300 *27:02, *27:04, *27:05
Threonine (T) 1.12 (1.03–1.21) 4.50 × 10−3 *13:02, *39:06, *40:06, *51:01, *51:08, *52:01, *55:01, *56:01
Arginine (R) 1.00 (Reference) 1 *15:01, *15:03, *15:10, *15:16, *15:17, *15:18, *18:01, *35:01, *35:02,
*35:03, *35:08, *35:12, *37:01, *38:01, *38:02, *39:01, *39:10, *40:01,
*41:01, *44:02, *44:03, *44:04, *44:05, *45:01, *47:01, *49:01, *50:01,
*53:01, *58:01
Tryptophan (W) 1.00 (0.89–1.12) 0.95 *14:01, *14:02
Serine (S) 0.86 (0.81–0.91) 4.81 × 10−8 *07:02, *07:05, *08:01, *15:07, *27:07, *40:02, *41:02, *48:01
Valine (V) 0.68 (0.59–0.78) 1.41 × 10−8 *57:01, *57:03