Figure 5. Kaplan–Meier analysis of OS and RFS in ICC with negative CA-199 based on CD86⁺/CD206⁺ TAMs.

(A) OS for integrated analysis of CD86⁺/CD206⁺ TAMs in 157 ICC patients with negative CA-199 (CA-199 ≤ 36 U/mL) and (B) RFS for integrated analysis of CD86⁺/CD206⁺ TAMs in 157 ICC patients with negative CA-199. Group I, high immunostaining density of CD86⁺ but low CD206⁺ TAMs; Group II, both low immunostaining density of CD86⁺ and CD206⁺ TAMs; Group III, both high immunostaining density of CD86⁺ and CD206⁺ TAMs; Group IV, low immunostaining density of CD86⁺ but high CD206⁺ TAMs. p Values were calculated by log-rank test, and p < 0.05 was considered statistically significant. OS, Overall survival; RFS, recurrence-free survival.