Table 3.
Model parameters selected as free-parameters by Morris Method
| Common Parameter | ATL | BAL | LA | MIA | NYC | SEA |
|---|---|---|---|---|---|---|
| 1.3 Population Dynamics - Mortality Rate | ||||||
| PLHIV (CD4 200-499) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| PLHIV (CD4 <200) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| PLHIV - PWID multiplier (CD4 200-499) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| PLHIV - PWID multiplier (CD4 <200) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| 2.1 Sexual Risk Behaviors - Number of Sexual Partner Multipliers | ||||||
| PWID relative to HET | ✓ | ✓ | ✓ | |||
| Decrease in sexual partners post-diagnosis | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| 2.2 Injection Risk Behaviors | ||||||
| Injection frequency | ✓ | ✓ | ✓ | ✓ | ||
| Decreased probability of injection sharing post-diagnosis | ✓ | ✓ | ✓ | ✓ | ||
| SSP effect on reducing injection sharing | ✓ | |||||
| 2.4 Probability of Transmission (per partnership) | ||||||
| Sex - Female to Male (CD4 ≥500) | ✓ | ✓ | ✓ | ✓ | ✓ | |
| Sex - Female to Male (CD4 200-499) | ✓ | |||||
| Sex - Female to Male (CD4 <200) | ✓ | ✓ | ||||
| Sex - Male to Female (CD4 ≥500) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Sex - Male to Female (CD4 200-499) | ✓ | |||||
| Sex - Male to Female (CD4 <200) | ✓ | |||||
| Sex - Male to Male (CD4 ≥500) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Sex - Male to Male (CD4 200-499) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Sex - Male to Male (CD4 <200) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Shared injection (CD4 ≥500) | ✓ | ✓ | ✓ | ✓ | ||
| Shared injection (CD4 200-499) | ✓ | |||||
| Shared injection (CD4 ≥200) | ✓ | |||||
| Transmission probability multiplier (Acute HIV) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| ART effect on reducing transmission - Sexual | ✓ | ✓ | ✓ | ✓ | ✓ | |
| ART effect on reducing transmission - Shared Injection | ✓ | |||||
| Condom effect on reducing transmission - Heterosexual Sex | ✓ | ✓ | ✓ | |||
| Condom effect on reducing transmission - Homosexual Sex | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| 3.1 HIV Testing - Annual Change in HIV Testing Rate | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| 3.5 HIV Disease Progression Transition Rate from Acute to Chronic HIV | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| City-Specific Parameter | ATL | BAL | LA | MIA | NYC | SEA |
| 2.1 Sexual Risk Behaviors - Number of Sexual Partners | ||||||
| Heterosexual partners, White, Low-risk MSM | ✓ | |||||
| Heterosexual partners, White, High-risk MSM | ✓ | ✓ | ||||
| Heterosexual partners, Black, High-risk MSM | ✓ | |||||
| Heterosexual partners, Hispanic, High-risk MSM | ✓ | |||||
| Heterosexual partners, Male, White, High-risk HET | ✓ | |||||
| Heterosexual partners, Male, Black, High-risk HET | ✓ | ✓ | ||||
| Heterosexual partners, Female, White, High-risk HET | ✓ | ✓ | ||||
| Heterosexual partners, Female, Black, High-risk HET | ✓ | |||||
| Heterosexual partners, Female, Hispanic, High-risk HET | ✓ | ✓ | ||||
| Homosexual partners, White, Low-risk MSM | ✓ | ✓ | ||||
| Homosexual partners, Black, Low-risk MSM | ✓ | ✓ | ✓ | |||
| Homosexual partners, White, High-risk MSM | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Homosexual partners, Black, High-risk MSM | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Homosexual partners, Hispanic, High-risk MSM | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| 2.1 Sexual Risk Behaviors - Condom Use Probability | ||||||
| Heterosexual, Male, White, High-risk HET | ✓ | |||||
| Homosexual, Male, White, Low-risk MSM | ✓ | |||||
| Homosexual, Male, Black, Low-risk MSM | ✓ | ✓ | ✓ | ✓ | ||
| Homosexual, Male, Hispanic, Low-risk MSM | ✓ | ✓ | ✓ | |||
| Homosexual, Male, White, High-risk MSM | ✓ | ✓ | ✓ | ✓ | ✓ | |
| Homosexual, Male, Black, High-risk MSM | ✓ | ✓ | ✓ | ✓ | ||
| Homosexual, Male, Hispanic, High-risk MSM | ✓ | ✓ | ✓ | ✓ | ||
| 2.1 Assortativeness of Heterosexual Partnership Paring, High-risk Black | ✓ | |||||
| 3.2 ART Initiation | ||||||
| Proportion linked to care post-diagnosis (CD4 ≥500), Male, Black, PWID | ✓ | |||||
| Proportion linked to care post-diagnosis (CD4 ≥500), Female, Black, PWID | ✓ | |||||
ATL: Atlanta; BAL: Baltimore; LA: Los Angeles; MIA: Miami; NYC: New York City; SEA: Seattle; Checked cells represent parameters selected for calibration.