Figure 10:

Changes in the TA physiologic stress-stretch state with age. (A) Changes with age in stretch experienced during the cardiac cycle ${\lambda }_{\theta }^{cardiaccycle}$ from diastole (80 mmHg) to systole (120 mmHg). (B) Circumferential θ (red) and longitudinal z (blue) physiologic stretches ${\lambda }_{phys}^{avg}$ and (C) stresses $t_{phys}^{avg}$ at 100 mmHg calculated using stress-free state as a reference; and (D) average physiologic stress per elastic lamellae unit in the circumferential (red) and longitudinal (blue) directions determined using ${\lambda }_z^{insitu}$ (solid lines) and ${\lambda }_z^{decoupling}$ (dashed lines).