Changes with age in elastin content evaluated using transverse (red) and longitudinal (blue) aortic sections. (A) density of elastin in the medial layer, (B) number of elastic lamellae in the medial layer, (C) thickness of the tunica media Hmedial, and (D) thickness of tunica media as a function of the number of elastic lamellae. Here boxes bound 25th and 75th percentiles for each age group, median and average values are marked with a vertical line and a dot within each box, whiskers extend to the 5th and 95th percentiles, and the outliers are displayed with a + sign.