Fig. 1.

Pediatric status epilepticus treatment algorithm combining current guidelines. This approach combines the timeline-based algorithm from current guidelines by Neurocritical Care Society [11], International League Against Epilepsy [14], the American Epilepsy Society [13], and information from institutional guidelines. See Tables 1 and 2 for further detailed dosing recommendations. Notably, the above are recommendations that should be customized for each patient based on individual case and seizure characteristics and institutional medication availability. ASM Anti-seizure medication, BZD benzodiazepine, EEG electro-encephalography, IM intramuscular, IN intranasal, IV intravenous, PE phenytoin-equivalent, POLG DNA polymerase gamma, SE status epilepticus