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. 2019 Dec 21;25(1):46. doi: 10.3390/molecules25010046

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Impact of P6 peptide, colchicine, and colchicine-P6 peptide conjugate treatments on human THP-1 macrophage cell viability at 24 h using the Cell Counting Kit-8 (CCK-8) assay. P6 peptide and colchicine-P6 peptide treatments (1, 10, and 25 μM) showed no significant difference in cell viability when compared with the control. Colchicine (1, 10, and 25 μM) dose-dependently reduced macrophage cell viability. Data are presented as scatter plots of three independent experiments with at least duplicate wells per treatment. Mean and standard deviations are highlighted. * p < 0.001; n.s.: non-significant.