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. 2019 Dec 19;25(1):15. doi: 10.3390/molecules25010015

Figure 3.

Figure 3

Effects of protopine on cell apoptosis in mice with LPS-induced AKI (n = 8 mice per group). (A) Effects of protopine on oxidative stress in mice with LPS-induced AKI. (B) Effects of protopine on apoptosis marker proteins in mice with LPS-induced AKI. * p < 0.05, ** p < 0.01 compared with the LPS group. (LPRO: low-dose protopine; MPRO: medium-dose protopine; HPRO: high-dose protopine; LPS: lipopolysaccharide; AKI: acute kidney injury; ROS: reactive oxygen species; FCM: flow cytometry; Bax: associated X protein; Bcl-2: B-cell lymphoma 2).