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. 2019 Dec 19;25(1):15. doi: 10.3390/molecules25010015

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of protopine on the blood cell subtype in mice with LPS-induced AKI (n = 8 mice per group). (A) Gating Strategy. (B) Effects of protopine on the blood cell subtype ratio in mice with LPS-induced AKI. (C,D) Effects of protopine on the ratio of CD45⁺Ly-6G⁺ and CD45⁺F4/80⁺ in mice with LPS-induced AKI. * p < 0.05, ** p < 0.01 compared with the LPS group. (LPRO: low-dose protopine; MPRO: medium-dose protopine; HPRO: high-dose protopine; LPS: lipopolysaccharide; AKI: acute kidney injury).