Table 1.
Antioxidant activities of compounds 1–7 in cell-based and cell-free assays.
| Compounds | ROS Level, % of Control | DPPH Scavenger Activity IC50, µM |
|
|---|---|---|---|
| Paraquat (PQ) | 6-OHDA | ||
| neurotoxin | 148.4. ± 6.9 | 139.2 ± 1.8 | - |
| 1a | 94.1 ± 4.1 | 132.9 ± 2.7 | 122.4 ± 7.1 |
| 1b | 83.2 ± 2.3 | 121.2 ± 1.6 | 118.1 ± 4.7 |
| 2 | 92.8 ± 2.4 | - | 23.6 [25] |
| 3 | 90.3 ± 2.2 | - | 29.9 [26] |
| 4 | 101.8 ± 7.6 | - | 34.0 [26] |
| 5 | 97.4 ± 2.8 | - | 31.1 [26] |
| 6 | 94.1 ± 2.9 | - | 46.0 [25] |
| 7 | 101.8 ± 7.6 | 95.4 ± 3.4 | 62.6 ± 1.1 |