Table 1.
Compound No | Name | IC50 a | |
---|---|---|---|
A2780 | SKOV3 | ||
1 | 6,7-dimethoxy-3′,4′-methylenedioxy-8- (3,3-dimethylallyl)isoflavone (DMI) |
0.45 ± 0.06 μM (0.18 ± 0.02 μg/mL) |
> 100 μM (> 39.41 μg/mL) |
2 | Ferrugone | 0.51 ± 0.06 μM (0.21 ± 0.02 μg/mL) |
36.78 ± 5.26 μM (15.01 ± 2.15 μg/mL) |
3 | Prebarbigerone | 32.06 ± 8.31 μM (13.16 ± 3.41 μg/mL) |
> 100 μM (> 41.05 μg/mL) |
- | Cisplatin b | 14.14 ± 0.59 μM (4.24 ± 0.18 μg/mL) |
36.64 ± 0.96 μM (10.99 ± 0.29 μg/mL) |
a IC50 values are defined as the concentration that results in a 50% decrease in the number of cells compared with that of the control cultures. b Cisplatin was used as a positive control.