Aβ |
amyloid-β |
ACh |
acetylcholine |
AChEI |
acetylcholinesterase inhibitor |
AD |
Alzheimer’s disease |
ChE |
cholinesterase |
EC50
|
half maximal effective concentration |
EeAChE |
acetylcholinesterase (from Electrophorus electricus) |
EfBChE |
butyrylcholinesterase (from Equus ferus) |
HsAChE |
acetylcholinesterase (from Homo sapiens) |
IC50
|
half maximal inhibitory concentration |
KOH |
potassium hydroxide |
MsOH |
methanesulfonic acid |
NMDA |
N-methyl-d-aspartate |
PIB |
Pittsburgh Compound B |
ROS |
reactive oxygen species |
SAR |
structure-activity relationship |
SDEV |
standard deviation |
TBDMS |
tert-butyldimethylsilyl |