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Results of cytotoxicity for gefitinib and regorafenib in RR-HCT116 and parental HCT116
| Drug | IC50 (µM) | Resistance index b | |
|---|---|---|---|
| RRa sub-line | HCT116 | ||
| gefitinib | 19.53±0.98 | 10.16±0.21 | 1.92 |
| regorafenib | 64.99±1.32 | 44.95±1.92 | 1.45 |
Radioresistant;
Ratio of IC50 drug dose in resistant sub-line to that in parental
