Table 1:
Quantification of T1, CBF, StO2, SaO2, OEF and CMRO2 in mouse (n = 5) and rat (n = 5) models during normothermia (37°C) and hypothermia (33°C). (mean ± SD; paired t-test)
| Mice | Rats | |||
|---|---|---|---|---|
| Mean ± SD | p-value | Mean ± SD | p-value | |
| T1 (ms) | ||||
| Normothermia | 2117±29 | 0.01 | 2203±141 | 0.06 |
| Hypothermia | 2017± 50 | 2122±135 | ||
| CBF (ml/100g/min) | ||||
| Normothermia | 200.1 ± 22.6 | 0.01 | 117.7 ± 25.8 | 0.1 |
| Hypothermia | 173.0 ± 29.8 | 93.6 ± 11.5 | ||
| StO2 | ||||
| Normothermia | 0.72 ± 0.03 | < 0.001 | 0.71 ± 0.02 | 0.1 |
| Hypothermia | 0.76 ± 0.03 | 0.73 ± 0.01 | ||
| SaO2 | ||||
| Normothermia | 0.97 ± 0.01 | 0.04 | 0.95 ± 0.03 | 0.9 |
| Hypothermia | 0.95 ± 0.03 | 0.95 ± 0.02 | ||
| OEF | ||||
| Normothermia | 0.33 ± 0.05 | 0.001 | 0.32 ± 0.02 | 0.4 |
| Hypothermia | 0.25 ± 0.06 | 0.30 ± 0.02 | ||
| CMRO2 (ml/100g/min) | ||||
| Normothermia | 7.8 ± 1.8 | 0.003 | 3.7 ± 0.9 | 0.03 |
| Hypothermia | 4.9 ± 1.1 | 2.5 ± 0.1 | ||