Table 2:
Values of CMRO2 (mean ± SD) from the literature, quantified by different methods in mouse and rat models under different anesthesia conditions
| Animal Model |
CMRO2 (ml/100g/min) |
Method | Anesthesia | Citation |
|---|---|---|---|---|
| Mouse | 6.3 ± 0.4 | 17O MRI | ketamine xylazine | (Zhu et al., 2013) |
| 6.5 ± 1.1 | 17O MRSI | Isoflurane | (Lou et al., 2016) | |
| 6.3 ± 0.5 | 15O PET | Isoflurane | (Temma et al., 2017) | |
| 3.6 ± 0.1 | BOLD fMRI | α-chloralose | (Hyder et al., 2000) | |
| 7.5 ± 0.4 | Morphine | |||
| Rat | 4.9 ± 0.8 | 17O MRSI | Ketamine | (Fiat and Kang, 1993) |
| 5.4 ± 0.4 | 17O MRSI | α-chloralose | (Zhu et al., 2007) | |
| 5.0 ± 0.4 | 15O microPET | α-chloralose | (Yee et al., 2006) | |